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This study provides an early report of the loss of glial cells within the PFC of patients with mood disorders, consistent with the hypothesized glutamate abnormalities in these disorders
Glutathione is found in virtually every cell of the body and plays a critical role in protein synthesis, enzyme function, transport, and cell maturation*
The incremental number of QALYs associated with SGLT2i use was projected at 29,357, and widespread use of SGLT2is was projected to lead to an incremental healthcare cost of AU$0.3 billion, resulting in an ICER of AU$8878 per QALY gained
doi: 10.1136/oemed-2014-102178 390
Both have substantial gastrointestinal side-effect profiles, but percentages from separate Wegovy and Zepbound clinical trial programs cannot be treated as a direct comparison
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